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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Corte. Para informações adicionais entre em contato com cnpgc.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Gado de Corte. |
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Data corrente: |
20/12/2007 |
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Data da última atualização: |
15/08/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
Internacional - A |
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Autoria: |
ANDREOTTI, R. |
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Afiliação: |
RENATO ANDREOTTI E SILVA, CNPGC. |
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Título: |
A synthetic bmti n-terminal fragment as antigen in bovine immunoprotection against the tick Boophilus microplus in a pen trial. |
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Ano de publicação: |
2007 |
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Fonte/Imprenta: |
Experimental Parasitology, v. 116, n. 1, p. 66-70, May 2007. |
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DOI: |
https://doi.org/10.1016/j.exppara.2006.11.009 |
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Idioma: |
Inglês |
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Notas: |
Na publicação: Renato Andreotti. |
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Conteúdo: |
Cattle tick control remains a serious problem in cattle farms worldwide, due to the limited success achieved with chemicals. Although the use of vaccines for tick control may open possibilities for an integrated approach, the search for other protective antigens is still necessary to improve control. Boophilus microplus is a rich source of BmTIs, serine proteinase inhibitors that are present throughout the tick's lifecycle. The present paper reports a pen trial conducted to evaluate the performance of a synthetic BmTI N-terminal fragment as antigen against the tick in bovines. The trial was conducted with two groups of eight crossbred cattle under controlled infestation: one group was vaccinated with BmTI peptide using saponin as adjuvant and the other was kept as control. Challenge was performed with 15,000 larvae. The specific IgG response was measured by ELISA, with successful outcomes for vaccinated animals. Vaccination resulted in an 18.4% level of efficacy when compared with the control group. |
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Thesagro: |
Boophilus Microplus; Bovino; Carrapato; Imunização; Inibidor de Proteína; Sanidade Animal. |
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Thesaurus NAL: |
Animal health; Antigens; Cattle; Immunization; Serine proteinases; Synthetic peptides; Tick control. |
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Categoria do assunto: |
-- |
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Marc: |
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001 1326267
005 2023-08-15
008 2007 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.exppara.2006.11.009$2DOI
100 1 $aANDREOTTI, R.
245 $aA synthetic bmti n-terminal fragment as antigen in bovine immunoprotection against the tick Boophilus microplus in a pen trial.
260 $c2007
500 $aNa publicação: Renato Andreotti.
520 $aCattle tick control remains a serious problem in cattle farms worldwide, due to the limited success achieved with chemicals. Although the use of vaccines for tick control may open possibilities for an integrated approach, the search for other protective antigens is still necessary to improve control. Boophilus microplus is a rich source of BmTIs, serine proteinase inhibitors that are present throughout the tick's lifecycle. The present paper reports a pen trial conducted to evaluate the performance of a synthetic BmTI N-terminal fragment as antigen against the tick in bovines. The trial was conducted with two groups of eight crossbred cattle under controlled infestation: one group was vaccinated with BmTI peptide using saponin as adjuvant and the other was kept as control. Challenge was performed with 15,000 larvae. The specific IgG response was measured by ELISA, with successful outcomes for vaccinated animals. Vaccination resulted in an 18.4% level of efficacy when compared with the control group.
650 $aAnimal health
650 $aAntigens
650 $aCattle
650 $aImmunization
650 $aSerine proteinases
650 $aSynthetic peptides
650 $aTick control
650 $aBoophilus Microplus
650 $aBovino
650 $aCarrapato
650 $aImunização
650 $aInibidor de Proteína
650 $aSanidade Animal
773 $tExperimental Parasitology$gv. 116, n. 1, p. 66-70, May 2007.
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